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Fri Jul 08, 2022

Cytotoxic Safety Cabinet

A cytotoxic safety cabinet, also known as a cytotoxic drug safety cabinet (CDSC) or a biological safety cabinet (BSC) for handling cytotoxic drugs, is a specialized type of laboratory equipment designed to provide a controlled environment for the safe handling and preparation of cytotoxic (antineoplastic) drugs.

Here are the key features and functions of a cytotoxic safety cabinet:

Containment: The cabinet is designed to contain hazardous aerosols and particles generated during the preparation of cytotoxic drugs, preventing their release into the laboratory environment.
Filtration: The cabinet typically includes high-efficiency particulate air (HEPA) filters to trap and remove contaminants from the air. Some cabinets may also have additional filters for handling volatile compounds.
Airflow: The cabinet provides a continuous flow of filtered air to maintain a clean work area. Airflow patterns are designed to minimize cross-contamination and protect both the operator and the environment.
Ergonomics: The design of the cabinet allows for comfortable and safe working conditions, including features such as armrests, adjustable work surfaces, and easy access to controls.
Monitoring Systems: Many cytotoxic safety cabinets are equipped with monitoring systems to ensure proper airflow and filter performance, alerting users to any malfunctions or safety breaches.
Decontamination: The cabinet surfaces are typically made of materials that are easy to clean and decontaminate to maintain a sterile working environment.

BIOHAZARD SAFETY CABINET Type A-2, Class II

Bio Safety Cabinet Class II Also Have An Open Front Design Provided With Negative Pressure Generation Module. This Equipment Provides Recirculation Of Mass Flow Of HEPA Filtered Air. This Type Of Bio Safety Cabinets Provides Excellent Protection To Users, Products And The Environment.

Construction
Bio Safety Cabinet Is Designed To Conform To The United State Federal Standard 209B/BS5295 And Meets The Class 100 Conditions Along With British Standard 5726-Appendix A. Our Units Are Fabricated Of Galvanized Iron Powder Coated/ Stainless Steel. The Side Panels Made Out Of Heavy Plexi Glass Sheets Are Mounted On Anodized Aluminum Frames. The Whole Unit Is Supplied With Manometer To Gauge The Pressure Drop In The Unit While Operation, Beside The Gas Cock, Power Socket Etc.

Filter Assembly
Fitted With Fully Washable Synthetic Pre-Filter Units And Secondary High Efficiency Perfect Air Filters Made Of Mini Pleated Non Woven Fabric. The Efficiency Of Our Filters Have A Rating Better Than 99.99% At DOP (Cold) And 99.97% At DOP (Hot). Our Units Have The Capacity To Hold All Suspended Particles Of Size > 0.3 Micron.

Motor And Blower Assembly:
Provided With Perfectly Balanced (Static As Well As Dynamic) Motor And Blower

Illumination:
Illumination At The Work Table By Means Of LED Lights Panel Concealed At The Upper Portion Of The Unit.

Ultra Violet Light Is Incorporated In The Illumination Panel Of Our Bio Safety Cabinets To Take Care Of The Sterilization Of The Existing Air Present In The Enclosure, Thus Ensuring The High Standard Of Cleanliness In Our Equipment Before The Commencement Of Actual Working.

Noise Level:
Our Bio Safety Is Designed To Ensure That The Work Enclosure Has Minimum Possible Vibration Levels And Noise Level Is Also Contained Below 70 db.

Biosafety cabinet class ii, type a2 specification:

Cleanliness	Class 100
Velocity	90 Feet / Min±20
Noise Level	65 Decibels ± 5% On A Scale
Particle Retention	0.1 Micron
Efficiency	99.999 %
Pressure Drop	23 mm Wg
Size-At Exhaust	6”x 6” x 6”
Pre-Filter	Non Woven-Synthetic Polyester
Particle Retention	10 -15 Micron
Efficiency	90%
Pressure Drop	6 mm Wg
Blower Assembly	By 1 No ¼ Hp, Single Phase, 1440 RPM Motor, Directly Coupled With A Pair Of Aluminum Centrifugal Impeller. Capacity 1000 CFM Pressure 30 mm Wg
Exhaust Assembly	By Motor of ¼ HP, Single Phase,1440 RPM Motor, Directly Coupled With A Aluminum Impeller. Capacity - 300 CFM, Ducting By PVC Pipe With 1 No ¼ HP Motor Blower With Rain Guard-Dia –150 mm
Ultra Violet Lamp	Philips/Osram Make
Illumination	LED
Standard Accessories	Pressure Manometer, Additional Power Point Gas Inlet Nozzle, And Floor Levelling Screws, Wire Cord
Power Supply	220 V, Single Phase, 50 Hz
Working Area	W 900 x D 600 x H 600mm W 1200 x D 600 x H 600mm W 1800 x D 600 x H 600mm

DESCRIPTION

BIOHAZARD SAFETY CABINET Type B2 Class II
This Type Of Biosafety Cabinet No Circulation Takes Places Inside Workspace And The Blower Will Exhaust All The 100% Of The Filtered Air.

Construction
Made Of Galvanized Iron Powder Coated / Stainless-Steel Sheet. The Work Zone Having Negative Pressure While A Microprocessor Controls Cabinet Functions. Further, An LCD Panel Is Fitted To Display The Monitoring Of The Cabinet Air Flow And A Blower Run Meter Is There To Track Operating Life.

Illumination
Fitted With Light With Optimal Wattage Ultra Violet Light To Ensure High Level Of Cleanliness Before Operation.

Noise Level
Deliver Extremely Low Noise Level Of Less Than 70 db And Also Provide Minimum Vibration Levels.

Filter Assembly
Equipped With Synthetic Pre-Filter Unit Washable And High-Efficiency Filters (Secondary) That Are Made Of Mini Pleated Hepa Non-Woven Fabric. The Filters Deliver An Efficiency Rating Which Is 99.99% At DOP (Cold) And 99.97% At DOP (Hot). Can Hold All Suspended Particles Of Size More Than 0.3 Micron.

Motor And Blower Assembly
Fitted With Balanced Motor And Blower. The Assembly Comes With The Rating Of ¼ HP.

In Addition To Normal Feature Of Biosafety Vertical Laminar Flow, It Is Provided With Following Unique Features:
100% Exhaust.
Sliding Sash - Renders Unit Convertible For Use As A Conventional Vertical Laminar Down Flow Clean Air Work Station
Filtered Exhaust - Protects Ambient Environment, And Avoids Build Up, Air Borne Particles.
Glove Ports And Gauntlets- Permits Working With Medium To High Risk Organisms, Pathogenic Cultures Or That Tend To Aerosolize In Unknown Concentration
Built In U.V. Germicidal Light-Facilitates Sterilization Of Working Area Before And After Use
Cock-For Gas, Air Or Vacuum

Biosafety cabinet Class II, Type B2 Specification:

Cleanliness	Class 100
Velocity	90 Feet / Min±20
Noise Level	65 Decibels ± 5% On A Scale
Hepa Filter	Media Glass Fiber Paper-Imported
Particle Retention	0.1 Micron
Efficiency	99.999 %
Pressure Drop	23 mm Wg
Size-At Exhaust	6”x 6” x 6”
Pre-Filter	Non Woven-Synthetic Polyester
Particle Retention	10 -15 Micron
Efficiency	90%
Pressure Drop	6 mm Wg
Blower Assembly	By 1 No ¼ Hp, Single Phase, 1440 RPM Motor, Directly Coupled With A Pair Of Aluminum Centrifugal Impeller.Capacity 1000 CFM Pressure 30 mm Wg
Exhaust Assembly	By Motor of ¼ HP, Single Phase1440 RPM Motor, Directly Coupled With A Aluminum Impeller.Capacity -300 CFM, Ducting By PVC Pipe With 1 No ¼ HP Motor Blower With Rain Guard-Dia –150 mm
Ultra Violet Lamp	3 Feet, 30 Watt – Philips/Osram Make
Illumination	4 Feet 40 Watt-With Diffusers
Standard Accessories	Pressure Manometer, Additional Power Point Gas Inlet Nozzle, And Floor Leveling Screws, Wire Chord
Power Supply	220 V, Single Phase, 50 Hz
Working Area	W 900 x D 600 x H 600mm W 1200 x D 600 x H 600mm W 1800 x D 600 x H 600mm

Conclusion

Using a cytotoxic safety cabinet helps protect healthcare workers from exposure to hazardous drugs and ensures that the drugs are prepared in a sterile and controlled environment, reducing the risk of contamination and ensuring patient safety.